Dystrophic Calcification and Metastatic Calcification

Difference between Dystrophic Calcification and Metastatic Calcification

  Dystrophic Calcification Metastatic Calcification
1. Definition- Deposits of calcium salts in dead or degenerated tissue Definition- Deposits of calcium salts in normal tissue
2. Calcium Metabolism- Normal Calcium Metabolism- Deranged
3. Serum calcium level- Normal Serum calcium level- Hypercalcaemia
4. Reversibility- Generally irreversible Reversibility- Reversible upon correction of metabolic disorder
5. Causes- Necrosis (Caseous, liquefactive, fat), Infarct, thrombi, dead parasites, certain tumor, cyst Causes- Hyperparathyroidism, prolonged immobilization, hypervitaminosis D
6. Pathogenesis- Increased binding of phosphates with necrotic & degenerative tissue which in turn binds to Calcium forming Calcium phosphate precipitates Pathogenesis- Increased precipitates of Calcium phosphate, due to hypercalcemia at certain sites eg. Lungs, stomach, blood vessels, etc.
7. Prognosis- Generally better due to little septicemia Prognosis- Generally poor due to profound toxemia


Difference between Metaplasia and Dysplasia
Difference between Hypertrophy and Hyperplasia
Difference between Dry Gangrene and Wet Gangrene

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