‘Hydatidiform’ means a drop of water & a mole mean shapeless masses. It is defined as abnormal placenta characterize by –
It may be non-invasive or invasive 2 forms are in non-invasive type-
-Clinically condition appears in the 4-5 months of gestation, characterized by increased in uterine size, vaginal bleeding & history of the passage of grape-like masses per vaginam.
-Serial determination of β-hCG is elevated more in blood & urine as compared with the level in normal pregnancy.
-Pathological find in noninvasive & in invasive is different.
(a) Classic mole-
Grossly- it is enlarged, filled with grape-like vesicles up to 3 cm in diameter & vesicles contain clear water fluid.
Microscopically- large, round, oedematous villi with decreased vascularity, Trophoblastic proliferation in the form of masses.
(b) Partial Mole-
Grossly- the uterus is smaller than expected, but part of the placenta appears normal and the fetus is having multiple malformations.
Microscopically- some of the villi show oedematous change while others are normal. Trophoblastic proliferation is usually slight.
Grossly- invasive mole shows the invasion of tissues into the uterine wall which causes hemorrhage.
Microscopically- usually lesion is benign & identical to classic mole, there is an elevated β hCG level.
Leopold's Maneuvers or the Obstetric Grips are the movements or the actions carried out by an examiner during the abdominal…
There are 4 Chambers in a Heart, 2 superior chambers the atrium are the receiving chambers and 2 inferior ventricles…
The Heart is a vital organ in the human body that pumps blood and through the blood vessels transports oxygen…
Chorionic villi are the functional unit of the placenta which lies in between the basal plate or chorionic plate. After…
The placenta is a discoid shaped organ which is responsible for the exchange of waste and nutrient in between the…
Implantation means the attachment of the blastocyst with the endometrial wall. After the fertilization, blastocyst becomes differentiate into syncytiotrophoblast and…