Dystrophic Calcification | Metastatic Calcification | |
1. | Definition- Deposits of calcium salts in dead or degenerated tissue | Definition- Deposits of calcium salts in normal tissue |
2. | Calcium Metabolism- Normal | Calcium Metabolism- Deranged |
3. | Serum calcium level- Normal | Serum calcium level- Hypercalcaemia |
4. | Reversibility- Generally irreversible | Reversibility- Reversible upon correction of metabolic disorder |
5. | Causes- Necrosis (Caseous, liquefactive, fat), Infarct, thrombi, dead parasites, certain tumor, cyst | Causes- Hyperparathyroidism, prolonged immobilization, hypervitaminosis D |
6. | Pathogenesis- Increased binding of phosphates with necrotic & degenerative tissue which in turn binds to Calcium forming Calcium phosphate precipitates | Pathogenesis- Increased precipitates of Calcium phosphate, due to hypercalcemia at certain sites eg. Lungs, stomach, blood vessels, etc. |
7. | Prognosis- Generally better due to little septicemia | Prognosis- Generally poor due to profound toxemia |
Difference between Metaplasia and Dysplasia
Difference between Hypertrophy and Hyperplasia
Difference between Dry Gangrene and Wet Gangrene
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