onset ol labour
Throughout the pregnancy, there is hypertrophy (increase in the size of cells) and hyperplasia (increase in a number of cells) of uterine muscle fibers so it reaches about 35 c.m. in length, at term, and during pregnancy, there is irregular, involuntary, painless uterine contraction (Braxton hicks contraction) but at the onset of labour it becomes a change in intensity, frequency or in the duration which starts from a pacemaker of the uterus at tubal ostia in fundus region then it spread downwards.
The mother has a sudden burst of energy known as nesting 24 to 48 hours before the onset of labour.
The exact reason for the causes of the onset of labour is unknown but the various theories responsible for that are endocrinal, biochemical, or mechanical stretch pathways, these are as follows-
Endocrinal factors
Oestrogen peak theory-
Progesterone withdrawal theory-
Prostaglandins initiating theory-
Oxytocin theory-
Fetal placental theory-
Mechanical factors
Uterine distension theory-
Biochemical Factors
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