HELLP SYNDROME

Hellp-Syndrome

  • Haemolysis (H), elevated liver enzyme (EL) & low platelet count (LP) (<100000/mm3). A rare complication of pre-eclampsia. It may develop without maternal HTN.
  • It is manifested by nausea,vomiting,epigastric pain (right upper quadrant pain). Parenchymal necrosis of liver causes (SGPT & SGOT) elevation in hepatic enzymes (>70 IU/L) & bilirubin (>1.2 mg/dl)

Management

  • Principle management are same as pre-eclampsia with magnesium sulphate is started
  • Caesarean section is common mode of delievery
  • Platelet transfusion can be given if count is <50,000/mm3
  • When pregnancy <34 weeks, bed rest, plasma volume expansion ,antithrombotic agent (dipyridamole), immunosuppressive agents (steroids)
  • Patient should be managed in an ICU until there is improvement in platelet count, urine output, B.P, liver enzymes.