Leiomyoma or fibromyoma, commonly called fibroids, is most common uterine tumours of smooth muscle origin, mixed with fibrous tissue component.
Majority of them are benign and cause no symptoms and symptomatic cases produce abnormal uterine bleeding, pain,due to compression of surrounding structures. The cause is unknown but the possible factor is oestrogen which stimulate proliferation.
Morphological features– It is more frequently located in uterus with in the myometrium (Intramural and interstitial), serosa (sub serosal ) underneath the endometrium (submucosal), subserosal and sub mucosal may develop pedicles.
Grossly – These are multiple ,circumscribed,firm,nodular,grey white masses of variable size and on cut section it shows whorled pattern.
Histologically – It composed of 2 tissue element – whorled bundle of smooth muscle cells mixed with connective tissue.